Induction of Reparative Dentin Formation on Exposed Dental Pulp by Dentin Phosphophoryn/Collagen Composite

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Induction of Reparative Dentin Formation on Exposed Dental Pulp by Dentin Phosphophoryn/Collagen Composite

The ultimate goal of vital pulp therapy is to regenerate rapidly dentin possessing an excellent quality using a biocompatible, bioactive agent. Dentin phosphophoryn (DPP), the most abundant noncollagenous polyanionic protein in dentin, cross-linked to atelocollagen fibrils was applied to direct pulp capping in rats. After 1, 2, and 3 weeks, the teeth applied were examined on the induction of re...

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Reactionary and reparative dentin formation after pulp capping: Hydrogel vs. Dycal

Background: After indirect capping, injured odontoblasts generate reactionary dentin, whereas after direct capping of a pulp exposure pulp, cells stimulate the formation of reparative dentin. The aim of this study was to evaluate and compare the effects of two direct capping agents on pulp tissue reactions: Hydrogel (a bovine serum albumin (BSA)/glutaraldehyde,) and Dycal (a calcium hydroxide-b...

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Dentin phosphophoryn promotes cellular migration of human dental pulp cells.

Dentin phosphophoryn (DPP) is a dentin sialophosphoprotein gene product that has an RGD motif and repeat sequences of aspartic acid and phosphoserine. To date, the function of DPP in the early stage of reparative dentin formation still remains unclear. The objective of this study was to evaluate the effects of DPP on pulp cell migration and proliferation. DPP promoted cell migration in a concen...

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Responses of the pulp–dentin organ to dental restorative biomaterials

Placement of a restorative material in dentin produces the possibility of pulpal injury. In vitro studies have shown that the constituents of dental biomaterials have toxic potentials. In the clinical setting, there may be an immediate reaction of the pulp to, for example, acid etching and to the placement of a bonding agent; however, in most cases the remaining dentin serves as protection agai...

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Cytotoxicity evaluation of dentin bonding agents by dentin barrier test on 3-dimensional pulp cells.

OBJECTIVE The aim of this study was to evaluate the effects of 4 dentin-bonding agents on the cell viability of bovine derived cells. STUDY DESIGN Cytotoxicity of dentin-bonding agents (G-Bond [GB], Adper Prompt Self-Etch [APSE], Clearfil DC Bond System [CDCB], and Quadrant University-1-Bond [UB]) was analyzed with a dentin barrier test device using 3-dimensional (3D) pulp cell cultures. A co...

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ژورنال

عنوان ژورنال: BioMed Research International

سال: 2014

ISSN: 2314-6133,2314-6141

DOI: 10.1155/2014/745139